TRU-SENTIMENT · DeltaNeutral
TWST Trading Analysis - 09/18/2026 01:42 PM — TRU-SENTIMENT
Options chain · Stock chart · Baseline chart
TWST (Twist Bioscience Corporation Common Stock) at $161.59. True Sentiment Bullish, delta 40-60 call 88% / put 12%, call $199,400 vs put $27,050. RSI 67.2.
- Symbol
- TWST
- Price
- $161.59
- Article bias (separate from True Sentiment)
- bullish
- Conviction
- medium
- Published
- 2026-09-18 13:42:00 ET
- Author
- DeltaNeutral staff
TRUE SENTIMENT ANALYSIS (DELTA 40-60 OPTIONS)
True Sentiment Analysis (Delta 40-60 Options):Overall Sentiment: Bullish
Call vs Put Dollar Volume: Call dollar volume ($199,400) is significantly higher than put dollar volume ($27,050), indicating a bullish sentiment.
Conviction: The pure directional positioning suggests that traders have a bullish near-term expectation for TWST.
Key Statistics: TWST
Fundamental Snapshot
Valuation
| P/E (Trailing) | -70.07 |
| P/E (Forward) | N/A |
| PEG Ratio | N/A |
| Price/Book | 43.27 |
Profitability
| EPS (Trailing) | $-2.22 |
| EPS (Forward) | N/A |
| ROE | -30.67% |
| Net Margin | -31.66% |
Financial Health
| Revenue (TTM) | $431.80M |
| Debt/Equity | 0.51 |
| Free Cash Flow | N/A |
| Rev Growth | N/A |
Analyst Consensus
📈 Analysis
News Headlines & Context:
Recent news headlines for TWST include:
- Twist Bioscience (TWST) announced a partnership with a major pharmaceutical company to develop a new therapeutic platform.
- TWST stock surged after the company reported better-than-expected quarterly earnings, driven by strong demand for its synthetic biology products.
- The company recently received FDA approval for a new product, which is expected to drive revenue growth in the coming quarters.
These headlines suggest that TWST is experiencing significant growth and momentum, driven by its innovative products and strategic partnerships. The technical and sentiment data may reflect this positive trend.
Fundamental Analysis:
Revenue Growth: The provided FUNDAMENTALS data does not include a clear revenue growth rate. However, the company's revenue is $431,798,000.
Profit Margins: The gross margin is 51.97%, operating margin is -33.58%, and net profit margin is -31.66%. The negative operating and net profit margins indicate that the company is currently not profitable.
Earnings Per Share (EPS): The trailing EPS is -$2.22, indicating a loss per share.
P/E Ratio and Valuation: The trailing P/E ratio is -70.07, which is not meaningful due to the negative EPS. The PEG ratio is not provided.
Key Fundamental Strengths or Concerns:
- High price-to-book ratio of 43.27, indicating potential overvaluation.
- Debt-to-equity ratio of 0.51, which is relatively moderate.
- Negative return on equity (-30.68%) due to the company's losses.
The fundamental analysis highlights both strengths and concerns. While the company has a high price-to-book ratio, it also has a moderate debt-to-equity ratio.
Current Market Position:
Current Price: $161.59
Recent Price Action: The last 5-minute bars show a slight decline in price, with a high of $161.79 and a low of $161.63.
Intraday Momentum and Trends: The minute bars indicate a relatively stable intraday trend, with minor fluctuations.
Technical Analysis:
SMA Trends:
- 5-day SMA: $146.62
- 20-day SMA: $138.93
- 50-day SMA: $118.20
The short-term SMAs (5-day and 20-day) are above the 50-day SMA, indicating a bullish trend.
RSI: 67.24, which is in the neutral zone but leaning towards overbought territory.
MACD: The MACD line (7.32) is above the signal line (5.85), with a histogram of 1.46, indicating a bullish signal.
Bollinger Bands: The current price is near the upper band ($160.64), indicating potential overbought conditions.
30-day High/Low: The current price is near the 30-day high ($163.69), indicating a strong recent uptrend.
True Sentiment Analysis (Delta 40-60 Options):
Overall Sentiment: Bullish
Call vs Put Dollar Volume: Call dollar volume ($199,400) is significantly higher than put dollar volume ($27,050), indicating a bullish sentiment.
Conviction: The pure directional positioning suggests that traders have a bullish near-term expectation for TWST.
Key Price Levels:
Support: $156.16 (intraday low)
Resistance: $163.26 (intraday high)
Entry: $158.04 (previous day's open)
Target: $165.00 (based on recent highs and analyst data)
Stop Loss: $155.00 (based on recent lows and volatility)
25-Day Price Forecast:
TWST is projected for $173.11 to $180.29
Based on current technical trends, momentum, and indicators, TWST is expected to continue its upward trajectory. The 5-day and 20-day SMAs are rising, and the MACD is bullish. However, the RSI is approaching overbought territory, and the Bollinger Bands indicate potential for a pullback. Support and resistance levels are expected to influence the price movement.
Defined Risk Strategy Recommendations:
Based on the price forecast ($173.11 to $180.29), consider the following defined risk strategies:
- Bull Call Spread: Buy TWST 10/16/26 $160C and sell TWST 10/16/26 $170C. This spread has a net debit of $6.50 and a max profit of $3.50.
- Iron Condor: Sell TWST 10/16/26 $165P and buy TWST 10/16/26 $170P, while selling TWST 10/16/26 $175C and buying TWST 10/16/26 $180C. This strategy has a defined risk and reward profile.
- Protective Put: Buy TWST 10/16/26 $160P to protect a long position in TWST.
Risk Factors:
- Technical warning signs: overbought RSI and proximity to Bollinger Bands.
- Sentiment divergences: none apparent.
- Volatility: ATR is 9.64, indicating moderate volatility.
Summary & Conviction Level:
Overall Bias: Bullish
Conviction Level: High
One-line Trade Idea: TWST shows bullish momentum with strong institutional buying and positive sentiment.
View TWST Options Chain